The era of multi-messenger astronomy is well and truly upon us, with 90 compact binaries observed since the Advanced LIGO detectors saw first light in 2015. Despite our very own cosmic backyard, the Milky Way, being ripe with prospective sources for ground-based gravitational wave detectors, the closest source detected thus far (GW170817, the famed binary neutron star merger) was at a distance of 40 Mpc. In this talk, I will outline a number of prospective Galactic multi-messenger sources, and discuss several ways in which their detection over the next twenty years can be improved through both experimental and analytical techniques.